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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STAT1
All Species:
10.61
Human Site:
S727
Identified Species:
29.17
UniProt:
P42224
Number Species:
8
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42224
NP_009330.1
750
87335
S727
T
D
N
L
L
P
M
S
P
E
E
F
D
E
V
Chimpanzee
Pan troglodytes
XP_511505
786
90098
E742
G
N
N
G
E
G
A
E
P
S
A
G
G
Q
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848353
750
87263
S727
T
D
N
L
L
P
M
S
P
E
E
F
D
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P42225
749
87179
S727
T
D
N
L
L
P
M
S
P
E
E
F
D
E
M
Rat
Rattus norvegicus
P52631
770
88021
E745
G
N
N
G
E
G
A
E
P
S
A
G
G
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6DV79
771
88152
E746
G
N
S
S
E
G
A
E
A
N
A
G
G
Q
F
Frog
Xenopus laevis
Q7ZXK3
766
87581
P736
F
D
S
V
M
Q
F
P
G
E
G
S
E
S
G
Zebra Danio
Brachydanio rerio
NP_571555
749
86838
E724
N
L
M
P
M
S
P
E
V
Y
G
E
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24151
761
86396
S739
T
P
H
H
A
Q
E
S
M
Q
L
G
N
G
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
N.A.
96.2
N.A.
92.2
51.5
N.A.
N.A.
50.9
50.7
61
N.A.
25.2
N.A.
N.A.
N.A.
Protein Similarity:
100
69.5
N.A.
98.2
N.A.
94.9
70.7
N.A.
N.A.
70.4
70.5
78.1
N.A.
46.7
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
100
N.A.
93.3
13.3
N.A.
N.A.
0
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
26.6
N.A.
N.A.
20
40
13.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
34
0
12
0
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
45
0
0
0
0
0
0
0
0
0
0
34
0
12
% D
% Glu:
0
0
0
0
34
0
12
45
0
45
34
12
12
45
0
% E
% Phe:
12
0
0
0
0
0
12
0
0
0
0
34
0
0
34
% F
% Gly:
34
0
0
23
0
34
0
0
12
0
23
45
34
12
12
% G
% His:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
34
34
0
0
0
0
0
12
0
12
0
0
% L
% Met:
0
0
12
0
23
0
34
0
12
0
0
0
0
0
12
% M
% Asn:
12
34
56
0
0
0
0
0
0
12
0
0
12
0
0
% N
% Pro:
0
12
0
12
0
34
12
12
56
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
23
0
0
0
12
0
0
0
34
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
0
0
23
12
0
12
0
45
0
23
0
12
0
12
0
% S
% Thr:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _